P2RY2 Antibody

• Background:

  The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene.

• NCBI Gene ID:

  5029

• Swiss Prot:

  P41231

• Accession Number:

  P41231

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This P2RY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-352 amino acids from the C-terminal region of human P2RY2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  42 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  P2RY2

• NCBI Official Name:

  P2Y purinoceptor 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Boucher, I., et al. Am. J. Physiol., Cell Physiol. 299 (2), C411-C421 (2010) :

• Background Reference 03:

  Ratchford, A.M., et al. J. Biol. Chem. 285 (10) :7545-7555 (2010)

• Background Reference 04:

  Taboubi, S., et al. Mol. Biol. Cell 21 (6) :946-955 (2010)

• Other Product Names:

  P2Y purinoceptor 2, P2Y2, ATP receptor, P2U purinoceptor 1, P2U1, P2U receptor 1, Purinergic receptor, P2RY2, P2RU1

• Tested Applications:

  WB

• Protein ID:

  311033490

• Physical Properties:

  Liquid