P2RY1 Antibody

CAT: 0223-57-841Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-841Size:400 µL
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Background
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq].
NCBI Gene ID
5028
Swiss Prot
P47900
Accession Number
P47900
Host
Rabbit
Reactivity
Human
Immunogen
This P2RY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the Central region of human P2RY1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
P2RY1
NCBI Official Name
P2Y purinoceptor 1
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Maloney, S.F., et al. Integr Biol (Camb) 2 (4) :183-192 (2010)
Background Reference 03
Nisar, S., et al. Traffic 11 (4) :508-519 (2010)
Background Reference 04
Kumar, T.S., et al. J. Med. Chem. 53 (6) :2562-2576 (2010)
Other Product Names
P2Y purinoceptor 1, P2Y1, ATP receptor, Purinergic receptor, P2RY1
Tested Applications
WB
Protein ID
1352692
Physical Properties
Liquid

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