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NFYC Antibody

CAT: 0223-58-221Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-221Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
4802
Swiss Prot
Q13952
Accession Number
Q13952
Host
Rabbit
Reactivity
Human
Immunogen
This NFYC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-129 amino acids from the N-terminal region of human NFYC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NFYC
NCBI Official Name
Nuclear transcription factor Y subunit gamma
NCBI Organism
Homo sapiens
Background Reference 01
Ichikawa, S., et al. J. Bone Miner. Res. 25 (8) :1821-1829 (2010)
Background Reference 02
Murai-Takeda, A., et al. J. Biol. Chem. 285 (11) :8084-8093 (2010)
Background Reference 03
Ceribelli, M., et al. J. Biol. Chem. 284 (49) :34189-34200 (2009)
Background Reference 04
Yamanaka, K., et al. Genomics 94 (4) :219-227 (2009)
Other Product Names
Nuclear transcription factor Y subunit gamma, CAAT box DNA-binding protein subunit C, Nuclear transcription factor Y subunit C, NF-YC, Transactivator HSM-1/2, NFYC
Tested Applications
WB
Protein ID
20137773
Physical Properties
Liquid

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