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NFYB Antibody

CAT: 0223-57-655Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-655Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.
NCBI Gene ID
4801
Swiss Prot
P25208
Accession Number
P25208
Host
Rabbit
Reactivity
Human
Immunogen
This NFYB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human NFYB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Symbol
NFYB
NCBI Official Name
Nuclear transcription factor Y subunit beta
NCBI Organism
Homo sapiens
Background Reference 01
Stros, M., et al. Nucleic Acids Res. 37 (7) :2070-2086 (2009)
Background Reference 02
Kang, J.H., et al. J. Cell. Biochem. 104 (4) :1192-1203 (2008)
Background Reference 03
Raju, C.S., et al. Mol. Biol. Cell 19 (7) :3008-3019 (2008)
Background Reference 04
Di Agostino, S., et al. Cancer Cell 10 (3) :191-202 (2006)
Other Product Names
Nuclear transcription factor Y subunit beta, CAAT box DNA-binding protein subunit B, Nuclear transcription factor Y subunit B, NF-YB, NFYB, HAP3
Tested Applications
WB, IF
Protein ID
399193
Physical Properties
Liquid

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