CDH3 Antibody

CAT: 0223-58-156Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-156Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CDH3 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in the gene encoding CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.
NCBI Gene ID
1001
Swiss Prot
P22223
Accession Number
P22223
Host
Rabbit
Reactivity
Human
Immunogen
This CDH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-142 amino acids from the N-terminal region of human CDH3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
91 kDa
Fragment
Rabbit Ig
Symbol
CDH3
NCBI Official Name
Cadherin-3
NCBI Organism
Homo sapiens
Background Reference 01
Indelman, M., Clin. Exp. Dermatol. 32 (2), 191-196 (2007)
Background Reference 02
Paredes, J., Clin. Cancer Res. 11 (16), 5869-5877 (2005)
Other Product Names
Cadherin-3, Placental cadherin, P-cadherin, CDH3, CDHP
Tested Applications
WB, IHC-P, Flow
Protein ID
146345382
Physical Properties
Liquid

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