CDH3 Antibody

• Background:

  CDH3 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in the gene encoding CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.

• NCBI Gene ID:

  1001

• Swiss Prot:

  P22223

• Accession Number:

  P22223

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CDH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-142 amino acids from the N-terminal region of human CDH3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  91 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CDH3

• NCBI Official Name:

  Cadherin-3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Indelman, M., Clin. Exp. Dermatol. 32 (2), 191-196 (2007)

• Background Reference 02:

  Paredes, J., Clin. Cancer Res. 11 (16), 5869-5877 (2005)

• Other Product Names:

  Cadherin-3, Placental cadherin, P-cadherin, CDH3, CDHP

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  146345382

• Physical Properties:

  Liquid