CDH8 Antibody

CAT: 0223-57-427Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-427Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CDH8 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
NCBI Gene ID
1006
Swiss Prot
P55286
Accession Number
P55286
Host
Rabbit
Reactivity
Human
Immunogen
This CDH8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-63 amino acids from the N-terminal region of human CDH8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
88 kDa
Fragment
Rabbit Ig
Symbol
CDH8
NCBI Official Name
Cadherin-8
NCBI Organism
Homo sapiens
Background Reference 01
Blaschke, S., Int. J. Cancer 101 (4), 327-334 (2002)
Background Reference 02
Shimoyama, Y., Biochem. J. 349 (PT 1), 159-167 (2000)
Other Product Names
Cadherin-8, CDH8
Tested Applications
WB, IHC-P
Protein ID
13432121
Physical Properties
Liquid

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