CDH7 Antibody

• Background :

  CDH7 is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures.This gene is a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures. Alternative splicing in the 5' UTR of this gene yields variant transcripts encoding the same protein.

• NCBI Gene ID :

  1005

• Swiss Prot :

  Q9ULB5

• Accession Number :

  NP_004352

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat, Dog, Zebrafish

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDH7.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Membrane

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CDH7 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  82 kDa, 88 kDa, 88 kDa, 89 kDa, 87 kDa

• Applications Notes :

  CDH7 antibody can be used for detection of CDH7 by ELISA at 1:12500. CDH7 antibody can be used for detection of CDH7 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  CDH7

• NCBI Official Name :

  Cadherin 7, type 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Moore, R., (2004) Oncogene 23 (40), 6726-6735.

• Other Product Names :

  CDH7, CDH7L1

• Tested Applications :

  ELISA, WB

• Protein ID :

  16306489

• Physical Properties :

  Liquid