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IHH Antibody

CAT: 0223-58-107Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-107Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.
NCBI Gene ID
3549
Swiss Prot
Q14623
Accession Number
Q14623
Host
Rabbit
Reactivity
Human
Immunogen
This IHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-80 amino acids from the N-terminal region of human IHH.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Symbol
IHH
NCBI Official Name
Indian hedgehog protein
NCBI Organism
Homo sapiens
Background Reference 01
Meulenbelt, I., et al. Ann. Rheum. Dis. (2010) In press :
Background Reference 02
Kang, S.J., et al. Hum. Mol. Genet. 19 (13) :2725-2738 (2010)
Background Reference 03
Okada, Y., et al. Hum. Mol. Genet. 19 (11) :2303-2312 (2010)
Background Reference 04
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Other Product Names
Indian hedgehog protein, IHH, HHG-2, Indian hedgehog protein N-product, Indian hedgehog protein C-product, IHH
Tested Applications
WB, IHC-P
Protein ID
33112634
Physical Properties
Liquid

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