TRIM27 Antibody

CAT: 0223-58-074Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-074Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.
NCBI Gene ID
5987
Swiss Prot
P14373
Accession Number
P14373
Host
Rabbit
Reactivity
Human
Immunogen
This TRIM27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-482 amino acids from the C-terminal region of human TRIM27.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TRIM27
NCBI Official Name
Zinc finger protein RFP
NCBI Organism
Homo sapiens
Background Reference 01
Johnson, A.D., et al. Nat. Genet. 42 (7) :608-613 (2010)
Background Reference 02
Barcellos, L.F., et al. PLoS Genet. (10), E1000696 (2009) :
Background Reference 03
Tezel, G.G., et al. Pathol. Res. Pract. 205 (6) :403-408 (2009)
Background Reference 04
Li, X., et al. Virology 360 (2) :419-433 (2007)
Other Product Names
Zinc finger protein RFP, 632-, RING finger protein 76, Ret finger protein, Tripartite motif-containing protein 27, TRIM27, RFP, RNF76
Tested Applications
WB
Protein ID
132517
Physical Properties
Liquid

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