TRIM22 Antibody

• Background:

  The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  10346

• Swiss Prot:

  Q8IYM9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 215-411 of human TRIM22 (NP_006065.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Chemokines & Cytokines, Immunology, Innate Immunity, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 57kDa

• Fragment:

  IgG

• Symbol:

  TRIM22

• NCBI Official Name:

  Tripartite motif containing 22

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TRIM22, GPSTAF50, RNF94, STAF50

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid