TRIM26 Antibody

• Background:

  The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6.

• NCBI Gene ID:

  7726

• Swiss Prot:

  Q12899

• Accession Number:

  Q12899

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TRIM26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-169 amino acids from the N-terminal region of human TRIM26.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  62 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  TRIM26

• NCBI Official Name:

  Tripartite motif-containing protein 26

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cree, B.A., et al. PLoS ONE (6), E11296 (2010) :

• Background Reference 02:

  Barcellos, L.F., et al. PLoS Genet. (10), E1000696 (2009) :

• Background Reference 03:

  Males, S., et al. Antivir. Ther. (Lond.) 12 (5) :797-803 (2007)

• Background Reference 04:

  Reymond, A., et al. EMBO J. 20 (9) :2140-2151 (2001)

• Other Product Names:

  Tripartite motif-containing protein 26, Acid finger protein, AFP, RING finger protein 95, Zinc finger protein 173, TRIM26, RNF95, ZNF173

• Tested Applications:

  WB

• Protein ID:

  17380344

• Physical Properties:

  Liquid