LDB1 Antibody

• Background:

  LDB1 binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. May play a role in the development of motor neurons. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity) .

• NCBI Gene ID:

  8861

• Swiss Prot:

  Q86U70

• Accession Number:

  Q86U70

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This LDB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-379 amino acids from the C-terminal region of human LDB1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Zebrafish, Chicken, Mouse, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  47 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  LDB1

• NCBI Official Name:

  LIM domain-binding protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Howard, P.W., et al. Biochem. Biophys. Res. Commun. 396 (3) :674-678 (2010)

• Background Reference 02:

  Howard, P.W., et al. Biochem. J. 429 (1) :127-136 (2010)

• Background Reference 03:

  Bhati, M., et al. EMBO J. 27 (14) :2018-2029 (2008)

• Background Reference 04:

  Ryan, D.P., et al. Proteins 70 (4) :1461-1474 (2008)

• Other Product Names:

  LIM domain-binding protein 1, LDB-1, Carboxyl-terminal LIM domain-binding protein 2, CLIM-2, LIM domain-binding factor CLIM2, hLdb1, Nuclear LIM interactor, LDB1, CLIM2

• Tested Applications:

  WB

• Protein ID:

  158518615

• Physical Properties:

  Liquid