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LDB1 Antibody

CAT: 0223-58-052Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-052Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LDB1 binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. May play a role in the development of motor neurons. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity) .
NCBI Gene ID
8861
Swiss Prot
Q86U70
Accession Number
Q86U70
Host
Rabbit
Reactivity
Human
Immunogen
This LDB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-379 amino acids from the C-terminal region of human LDB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Zebrafish, Chicken, Mouse, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LDB1
NCBI Official Name
LIM domain-binding protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Howard, P.W., et al. Biochem. Biophys. Res. Commun. 396 (3) :674-678 (2010)
Background Reference 02
Howard, P.W., et al. Biochem. J. 429 (1) :127-136 (2010)
Background Reference 03
Bhati, M., et al. EMBO J. 27 (14) :2018-2029 (2008)
Background Reference 04
Ryan, D.P., et al. Proteins 70 (4) :1461-1474 (2008)
Other Product Names
LIM domain-binding protein 1, LDB-1, Carboxyl-terminal LIM domain-binding protein 2, CLIM-2, LIM domain-binding factor CLIM2, hLdb1, Nuclear LIM interactor, LDB1, CLIM2
Tested Applications
WB
Protein ID
158518615
Physical Properties
Liquid

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