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Mouse Frk Antibody

CAT: 0223-58-031Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-031Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity) .
NCBI Gene ID
14302
Swiss Prot
Q922K9
Accession Number
Q922K9
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Frk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-491 amino acids from the C-terminal region of mouse Frk.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Frk
NCBI Official Name
Tyrosine-protein kinase FRK
NCBI Organism
Mus musculus
Background Reference 01
Akerblom, B., et al. Mol. Cell. Endocrinol. 270 (1-2), 73-78 (2007) :
Background Reference 02
Nishimura, M., et al. DNA Res. 11 (5) :315-323 (2004)
Background Reference 03
Sharov, A.A., et al. PLoS Biol. (3), E74 (2003) :
Background Reference 04
Cowen, M.S., et al. Alcohol. Clin. Exp. Res. 27 (8) :1213-1219 (2003)
Other Product Names
Tyrosine-protein kinase FRK, Beta-cell Src-homology tyrosine kinase, BSK, FYN-related kinase, Intestine tyrosine kinase, Frk, Bsk, Iyk
Tested Applications
WB
Physical Properties
Liquid

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