CD106 Antibody

• Background:

  This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

• NCBI Gene ID:

  7412

• Swiss Prot:

  P19320

• Accession Number:

  P19320

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CD106 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 amino acids from the Central region of human CD106.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  81 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  VCAM1

• NCBI Official Name:

  Vascular cell adhesion protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Beckers, M.M., et al. Eur. J. Intern. Med. 21 (4) :289-292 (2010)

• Background Reference 03:

  Jin, C., et al. Coron. Artery Dis. 21 (5) :273-277 (2010)

• Background Reference 04:

  Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)

• Other Product Names:

  Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, INCAM-100, CD106, VCAM1, L1CAM

• Tested Applications:

  WB

• Protein ID:

  137560

• Physical Properties:

  Liquid