CD106 Antibody

• Background :

  This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

• NCBI Gene ID :

  7412

• Swiss Prot :

  P19320

• Accession Number :

  P19320

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This CD106 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 amino acids from the Central region of human CD106.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Neuroscience, Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  81 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  VCAM1

• NCBI Official Name :

  Vascular cell adhesion protein 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02 :

  Beckers, M.M., et al. Eur. J. Intern. Med. 21 (4) :289-292 (2010)

• Background Reference 03 :

  Jin, C., et al. Coron. Artery Dis. 21 (5) :273-277 (2010)

• Background Reference 04 :

  Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)

• Other Product Names :

  Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, INCAM-100, CD106, VCAM1, L1CAM

• Tested Applications :

  WB

• Protein ID :

  137560

• Physical Properties :

  Liquid