P2RX2 Antibody

• Background:

  P2RX2 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene.

• NCBI Gene ID:

  22953

• Swiss Prot:

  Q9UBL9-5

• Accession Number:

  NP_777361

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human P2RX2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store P2RX2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  42 kDa, 44 kDa, 49 kDa, 52 kDa, 55 kDa, 45 kDa

• Applications Notes:

  P2RX2 antibody can be used for detection of P2RX2 by ELISA at 1:312500. P2RX2 antibody can be used for detection of P2RX2 by western blot at 0.6 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  P2RX2

• NCBI Official Name:

  Purinergic receptor P2X, ligand-gated ion channel, 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Barrera, N.P., et al., (2005) J. Biol. Chem. 280 (11), 10759-10765.

• Other Product Names:

  P2RX2, P2X2, DFNA41

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  28416921

• Physical Properties:

  Liquid