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HMGB3 Antibody

CAT: 0223-57-896Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-896Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]) .
NCBI Gene ID
3149
Swiss Prot
O15347
Accession Number
O15347
Host
Rabbit
Reactivity
Human
Immunogen
This HMGB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the Central region of human HMGB3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HMGB3
NCBI Official Name
High mobility group protein B3
NCBI Organism
Homo sapiens
Background Reference 01
Nemeth, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 103 (37) :13783-13788 (2006)
Background Reference 02
Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)
Background Reference 03
Vaccari, T., et al. Genomics 49 (2) :247-252 (1998)
Background Reference 04
Wilke, K., et al. Gene 198 (1-2), 269-274 (1997) :
Other Product Names
High mobility group protein B3, High mobility group protein 2a, HMG-2a, High mobility group protein 4, HMG-4, HMGB3, HMG2A, HMG4
Tested Applications
WB
Physical Properties
Liquid

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