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HMGB2 Antibody

CAT: 0223-62-718Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-718Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V (D) J recombination.
NCBI Gene ID
3148
Swiss Prot
P26583
Accession Number
P26583
Host
Rabbit
Reactivity
Human
Immunogen
This HMGB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-118 amino acids from the Central region of human HMGB2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HMGB2
NCBI Official Name
High mobility group protein B2
NCBI Organism
Homo sapiens
Background Reference 01
Majumdar A., Brown D. 19:6643-6643 (1991)
Background Reference 02
Shirakawa H., Yoshida M.J.. 267:6641-6645 (1992)
Background Reference 03
Alexandre S., Li W.W.Nucleic Acids Res. 20:6413-6413 (1992)
Background Reference 04
Fan Z., Beresford P.J.Mol. Cell. Biol. 22:2810-2820 (2002)
Other Product Names
High mobility group protein B2, High mobility group protein 2, HMG-2, HMGB2, HMG2
Tested Applications
WB
Protein ID
123374
Physical Properties
Liquid

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