KCNC3 Antibody

• Background:

  The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes.

• NCBI Gene ID:

  3748

• Swiss Prot:

  Q14003

• Accession Number:

  Q14003

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This KCNC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639-667 amino acids from the C-terminal region of human KCNC3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  81 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  KCNC3

• NCBI Official Name:

  Potassium voltage-gated channel subfamily C member 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Figueroa, K.P., et al. Hum. Mutat. 31 (2) :191-196 (2010)

• Background Reference 02:

  Waters, M.F., et al. Cerebellum 7 (2) :165-169 (2008)

• Background Reference 03:

  Waters, M.F., et al. Nat. Genet. 38 (4) :447-451 (2006)

• Background Reference 04:

  Gutman, G.A., et al. Pharmacol. Rev. 57 (4) :473-508 (2005)

• Other Product Names:

  Potassium voltage-gated channel subfamily C member 3, KSHIIID, Voltage-gated potassium channel subunit Kv33, KCNC3

• Tested Applications:

  WB

• Protein ID:

  212276500

• Physical Properties:

  Liquid