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KCNC2 Antibody

CAT: 0223-57-320Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-320Size:400 µL
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Background
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Three transcript variants encoding three different isoforms have been found for this gene.
NCBI Gene ID
3747
Swiss Prot
Q96PR1
Accession Number
Q96PR1
Host
Rabbit
Reactivity
Mouse
Immunogen
This KCNC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 544-573 amino acids from the C-terminal region of human KCNC2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
70 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KCNC2
NCBI Official Name
Potassium voltage-gated channel subfamily C member 2
NCBI Organism
Homo sapiens
Background Reference 01
Wang, Z., et al. J. Gen. Physiol. 133 (4) :361-374 (2009)
Background Reference 02
Gutman, G.A., et al. Pharmacol. Rev. 57 (4) :473-508 (2005)
Background Reference 03
Haas, M., et al. Mamm. Genome 4 (12) :711-715 (1993)
Other Product Names
Potassium voltage-gated channel subfamily C member 2, Voltage-gated potassium channel Kv32, KCNC2
Tested Applications
WB
Protein ID
74752079
Physical Properties
Liquid

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