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KCNC4 Antibody

CAT: 0223-58-639Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-639Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene.
NCBI Gene ID
3749
Swiss Prot
Q03721
Accession Number
Q03721
Host
Rabbit
Reactivity
Human
Immunogen
This KCNC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-546 amino acids from the C-terminal region of human KCNC4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
70 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KCNC4
NCBI Official Name
Potassium voltage-gated channel subfamily C member 4
NCBI Organism
Homo sapiens
Background Reference 01
Mosing, M.A., et al. Twin Res Hum Genet 13 (4) :398-403 (2010)
Background Reference 02
Menendez, S.T., et al. J. Pathol. 221 (4) :402-410 (2010)
Background Reference 03
Leblanc, N. Cardiovasc. Res. 86 (3) :351-352 (2010)
Background Reference 04
Miguel-Velado, E., et al. Cardiovasc. Res. 86 (3) :383-391 (2010)
Other Product Names
Potassium voltage-gated channel subfamily C member 4, KSHIIIC, Voltage-gated potassium channel subunit Kv34, KCNC4
Tested Applications
WB
Protein ID
66774206
Physical Properties
Liquid