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PPM1G Antibody

CAT: 0223-57-704Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-704Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
NCBI Gene ID
5496
Swiss Prot
O15355
Accession Number
O15355
Host
Rabbit
Reactivity
Human
Immunogen
This PPM1G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the N-terminal region of human PPM1G.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPM1G
NCBI Official Name
Protein phosphatase 1G
NCBI Organism
Homo sapiens
Background Reference 01
Dick, D.M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (6), 1179-1188 (2010) :
Background Reference 02
Suh, E.J., et al. Biochem. Biophys. Res. Commun. 386 (3) :467-470 (2009)
Background Reference 03
Petri, S., et al. J. Cell Biol. 179 (3) :451-465 (2007)
Background Reference 04
Allemand, E., et al. Nat. Struct. Mol. Biol. 14 (7) :630-638 (2007)
Other Product Names
Protein phosphatase 1G, Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, PP2C-gamma, Protein phosphatase magnesium-dependent 1 gamma, PPM1G, PPM1C
Tested Applications
WB
Physical Properties
Liquid

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