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PPM1L Antibody

CAT: 0223-55-550Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-550Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PPM1L, or PP2CE, belongs to the PP2C group of serine/threonine phosphatases, which are distinguished from other phosphatases by their structure, absolute requirement for Mg (2+) or Mn (2+), and insensitivity to okadaic acid. PP2Cs regulate stress-activated protein kinase (SAPK; see MIM 601158) signaling cascades that respond to extracellular stimuli (Jin et al., 2004 [PubMed 15560375]) .
NCBI Gene ID
151742
Swiss Prot
Q5SGD2
Accession Number
Q5SGD2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PPM1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the C-terminal region of human PPM1L.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Symbol
PPM1L
NCBI Official Name
Protein phosphatase 1L
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Thean, L.F., et al. Genes Chromosomes Cancer 49 (2) :99-106 (2010)
Background Reference 03
Trynka, G., et al. Gut 58 (8) :1078-1083 (2009)
Background Reference 04
Saito, S., et al. J. Biol. Chem. 283 (10) :6584-6593 (2008)
Other Product Names
Protein phosphatase 1L, Protein phosphatase 1-like, Protein phosphatase 2C isoform epsilon, PP2C-epsilon, PPM1L, PP2CE
Tested Applications
WB, IHC-P
Protein ID
74743437
Physical Properties
Liquid

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