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GTF2B Antibody

CAT: 0223-57-669Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-669Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
NCBI Gene ID
2959
Swiss Prot
Q00403
Accession Number
Q00403
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This GTF2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human GTF2B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GTF2B
NCBI Official Name
Transcription initiation factor IIB
NCBI Organism
Homo sapiens
Background Reference 01
Wang, Y., et al. Curr. Biol. 20 (6) :548-553 (2010)
Background Reference 02
Thompson, N.E., et al. J. Biol. Chem. 284 (37) :24754-24766 (2009)
Background Reference 03
Gilman, B., et al. J. Biol. Chem. 284 (14) :9093-9098 (2009)
Background Reference 04
Vogt, C., et al. J. Virol. 82 (22) :11446-11453 (2008)
Other Product Names
Transcription initiation factor IIB, General transcription factor TFIIB, S300-II, GTF2B, TF2B, TFIIB
Tested Applications
WB
Protein ID
135629
Physical Properties
Liquid

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