GTF2B Antibody

• Background :

  This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.

• NCBI Gene ID :

  2959

• Swiss Prot :

  Q00403

• Accession Number :

  Q00403

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This GTF2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human GTF2B.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  35 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  GTF2B

• NCBI Official Name :

  Transcription initiation factor IIB

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Wang, Y., et al. Curr. Biol. 20 (6) :548-553 (2010)

• Background Reference 02 :

  Thompson, N.E., et al. J. Biol. Chem. 284 (37) :24754-24766 (2009)

• Background Reference 03 :

  Gilman, B., et al. J. Biol. Chem. 284 (14) :9093-9098 (2009)

• Background Reference 04 :

  Vogt, C., et al. J. Virol. 82 (22) :11446-11453 (2008)

• Other Product Names :

  Transcription initiation factor IIB, General transcription factor TFIIB, S300-II, GTF2B, TF2B, TFIIB

• Tested Applications :

  WB

• Protein ID :

  135629

• Physical Properties :

  Liquid