GTF2I Antibody

• Background:

  GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon (s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants.

• NCBI Gene ID:

  2969

• Swiss Prot:

  Q75M85

• Accession Number:

  NP_001509

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GTF2I.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GTF2I antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  108 kDa, 112 kDa, 110 kDa, 110 kDa

• Applications Notes:

  GTF2I antibody can be used for detection of GTF2I by ELISA at 1:312500. GTF2I antibody can be used for detection of GTF2I by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  GTF2I

• NCBI Official Name:

  General transcription factor IIi

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Desgranges, Z.P., (2005) Mol. Cell. Biol. 25 (24), 10940-10952.

• Other Product Names:

  GTF2I, WBS, DIWS, SPIN, IB291, BAP135, BTKAP1, TFII-I, WBSCR6, GTFII-I

• Tested Applications:

  ELISA, WB

• Protein ID:

  169881252

• Physical Properties:

  Liquid