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L3MBTL2 Antibody

CAT: 0223-57-579Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-579Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
NCBI Gene ID
83746
Swiss Prot
Q969R5
Accession Number
Q969R5
Host
Rabbit
Reactivity
Human
Immunogen
This L3MBTL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 627-656 amino acids from the C-terminal region of human L3MBTL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
79 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
L3MBTL2
NCBI Official Name
Lethal (3) malignant brain tumor-like protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Guo, Y., et al. Nucleic Acids Res. 37 (7) :2204-2210 (2009)
Background Reference 02
Lechtenberg, B.C., et al. Protein Sci. 18 (3) :657-661 (2009)
Background Reference 03
Trojer, P., et al. Cell 129 (5) :915-928 (2007)
Background Reference 04
Collins, J.E., et al. Genome Biol. (10), R84 (2004) :
Other Product Names
Lethal (3) malignant brain tumor-like protein 2, H-l (3) mbt-like protein 2, L (3) mbt-like protein 2, L3MBTL2
Tested Applications
WB
Protein ID
27734418
Physical Properties
Liquid

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