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L3MBTL Antibody

CAT: 0223-25-388Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-25-388Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
L3MBTL is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells.This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
26013
Swiss Prot
Q9Y468
Accession Number
NP_056293
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human L3MBTL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store L3MBTL antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
86 kDa
Applications Notes
L3MBTL antibody can be used for detection of L3MBTL by ELISA at 1:1562500. L3MBTL antibody can be used for detection of L3MBTL by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
L3MBTL1
NCBI Official Name
L (3) mbt-like 1 (Drosophila)
NCBI Organism
Homo sapiens
Background Reference 01
Min, J., (2007) Nat. Struct. Mol. Biol. 14 (12), 1229-1230.
Other Product Names
L3MBTL, DKFZp586P1522, FLJ41181, H-L (3) MBT, KIAA0681, L3MBTL1, dJ138B7.3, L3MBTL, ZC2HC3
Tested Applications
ELISA, WB
Protein ID
117938328
Physical Properties
Liquid

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