Products for Research Use Only

MLL5 Antibody

CAT: 0223-57-534Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-534Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized. [provided by RefSeq].
NCBI Gene ID
55904
Swiss Prot
Q8IZD2
Accession Number
Q8IZD2
Host
Rabbit
Reactivity
Human
Immunogen
This MLL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human MLL5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
205 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KMT2E
NCBI Official Name
Histone-lysine N-methyltransferase 2E
NCBI Organism
Homo sapiens
Background Reference 01
Liu, J., et al. J. Biol. Chem. 285 (27) :20904-20914 (2010)
Background Reference 02
Fujiki, R., et al. Nature 459 (7245) :455-459 (2009)
Background Reference 03
Cheng, F., et al. Int. J. Biochem. Cell Biol. 40 (11) :2472-2481 (2008)
Background Reference 04
Sun, X.J., et al. PLoS ONE (1), E1499 (2008) :
Other Product Names
Histone-lysine N-methyltransferase 2E, Lysine N-methyltransferase 2E, Myeloid/lymphoid or mixed-lineage leukemia protein 5, KMT2E, MLL5
Tested Applications
WB
Protein ID
74723669
Physical Properties
Liquid