MLL4 Antibody

• Background :

  MLL4 a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. MLL4 is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer

• NCBI Gene ID :

  9757

• Swiss Prot :

  Q9UMN6-2

• Accession Number :

  Q9UMN6-2

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MLL4.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Transcription, Cancer

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MLL4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  64 kDa, 294 kDa

• Applications Notes :

  MLL4 antibody can be used for detection of MLL4 by ELISA at 1:12500. MLL4 antibody can be used for detection of MLL4 by western blot at 5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  KMT2B

• NCBI Official Name :

  Lysine (K) -specific methyltransferase 2B

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  FitzGerald, K.T., et al., (1999) Genomics 59 (2), 187-192.

• Other Product Names :

  MLL4, HRX2, MLL2, MLL4, TRX2, WBP7, MLL1B

• Tested Applications :

  ELISA, WB

• Protein ID :

  12643900

• Physical Properties :

  Liquid