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NUP88 Antibody

CAT: 0223-57-528Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-528Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias.
NCBI Gene ID
4927
Swiss Prot
Q99567
Accession Number
Q99567
Host
Rabbit
Reactivity
Human
Immunogen
This NUP88 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 701-730 amino acids from the C-terminal region of human NUP88.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
84 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NUP88
NCBI Official Name
Nuclear pore complex protein Nup88
NCBI Organism
Homo sapiens
Background Reference 01
Hashizume, C., et al. Mol. Cancer 9, 119 (2010) :
Background Reference 02
Brustmann, H., et al. Ann Diagn Pathol 13 (5) :303-307 (2009)
Background Reference 03
Cheng, Y.T., et al. Plant Cell 21 (8) :2503-2516 (2009)
Background Reference 04
Andres-Hernando, A., et al. J. Biol. Chem. 283 (36) :25082-25090 (2008)
Other Product Names
Nuclear pore complex protein Nup88, 88 kDa nucleoporin, Nucleoporin Nup88, NUP88
Tested Applications
WB
Protein ID
25008854
Physical Properties
Liquid

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