NUP85 Antibody

• Background:

  This gene encodes a protein component of the Nup107-160 subunit of the nuclear pore complex. Nuclear pore complexes are embedded in the nuclear envelope and promote bidirectional transport of macromolecules between the cytoplasm and nucleus. The encoded protein can also bind to the C-terminus of chemokine (C-C motif) receptor 2 (CCR2) and promote chemotaxis of monocytes, thereby participating in the inflammatory response. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  79902

• Swiss Prot:

  Q9BW27

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 427-656 of human NUP85 (NP_079120.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HT-29

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 70kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  NUP85

• Positive Control 2:

  U-87MG

• Positive Control 3:

  A-549

• Positive Control 4:

  LO2

• Positive Control 5:

  HeLa

• Positive Control 6:

  Mouse brain

• NCBI Official Name:

  Nucleoporin 85kDa

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PCNT1, PCN, PCNT, pericentrin 1, frount, nucleoporin Nup75, nucleoporin 85 kDa, NUP85, NUP75, PCNT1

• Tested Applications:

  WB

• Physical Properties:

  Liquid