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NUP85 Antibody

CAT: 0223-61-273Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-61-273Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2- activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl- inositol 3-kinase-Rac-lammellipodium protrusion cascade.
NCBI Gene ID
79902
Swiss Prot
Q9BW27
Accession Number
Q9BW27
Host
Rabbit
Reactivity
Human
Immunogen
This NUP85 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 163-195 amino acids from human NUP85.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
75 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
NUP85
NCBI Official Name
Nuclear pore complex protein Nup85
NCBI Organism
Homo sapiens
Background Reference 01
Cronshaw J.M., et al.J. Cell Biol. 158:915-927 (2002) .
Background Reference 02
Terashima Y., et al.Nat. Immunol. 6:827-835 (2005) .
Background Reference 03
Ota T., et al.Nat. Genet. 36:40-45 (2004) .
Background Reference 04
Bechtel S., et al.BMC Genomics 8:399-399 (2007) .
Other Product Names
Nuclear pore complex protein Nup85, 85 kDa nucleoporin, FROUNT, Nucleoporin Nup75, Nucleoporin Nup85, Pericentrin-1, NUP85, NUP75, PCNT1
Tested Applications
WB
Protein ID
74733394
Physical Properties
Liquid

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