Mouse Ksr1 Antibody

• Background:

  Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.

• NCBI Gene ID:

  16706

• Swiss Prot:

  Q61097

• Accession Number:

  Q61097

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Mouse Ksr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 719-747 amino acids from the C-terminal region of mouse Ksr1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  97 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Ksr1

• NCBI Official Name:

  Kinase suppressor of Ras 1

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Costanzo-Garvey, D.L., et al. Cell Metab. 10 (5) :366-378 (2009)

• Background Reference 02:

  McKay, M.M., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (27) :11022-11027 (2009)

• Background Reference 03:

  Razidlo, G.L., et al. J. Biol. Chem. 284 (11) :6705-6715 (2009)

• Background Reference 04:

  Giurisato, E., et al. Mol. Cell. Biol. 29 (6) :1554-1564 (2009)

• Other Product Names:

  Kinase suppressor of Ras 1, mKSR1, Protein Hb, Ksr1, Ksr

• Tested Applications:

  WB

• Physical Properties:

  Liquid