Mouse BID Antibody

• Background:

  Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. Bid is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8) ; CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release.

• NCBI Gene ID:

  12122

• Swiss Prot:

  P70444

• Accession Number:

  P70444

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This mouse BID antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from mouse BID.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Obesity

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  22 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  Bid

• NCBI Official Name:

  BH3-interacting domain death agonist

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Ziporen, L., J. Immunol. 182 (1), 515-521 (2009)

• Background Reference 02:

  Kaufmann, T., Immunity 30 (1), 56-66 (2009)

• Background Reference 03:

  Mandal, M., Proc. Natl. Acad. Sci. U.S.A. 105 (52), 20840-20845 (2008)

• Other Product Names:

  BH3-interacting domain death agonist, p22 BID, BID, BH3-interacting domain death agonist p15, p15 BID, BH3-interacting domain death agonist p13, p13 BID, BH3-interacting domain death agonist p11, p11 BID, Bid

• Tested Applications:

  WB, IHC-P, Flow

• Physical Properties:

  Liquid