Mouse Bckdk Antibody

CAT: 0223-57-278Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-278Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex (By similarity) .
NCBI Gene ID
12041
Swiss Prot
O55028
Accession Number
O55028
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Mouse Bckdk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-188 amino acids from the Central region of mouse Bckdk.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Bckdk
NCBI Official Name
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial
NCBI Organism
Mus musculus
Background Reference 01
Pagliarini, D.J., et al. Cell 134 (1) :112-123 (2008)
Background Reference 02
Lee, J., et al. Mol. Cell Proteomics 6 (4) :669-676 (2007)
Background Reference 03
Hutson, S.M. Biochem. J. 400 (1), E1-E3 (2006) :
Background Reference 04
Joshi, M.A., et al. Biochem. J. 400 (1) :153-162 (2006)
Other Product Names
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial, Branched-chain alpha-ketoacid dehydrogenase kinase, BCKD-kinase, BCKDHKIN, Bckdk
Tested Applications
WB
Physical Properties
Liquid

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