Mouse Dyrk1a Antibody

• Background:

  Dyrk1a may play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates.

• NCBI Gene ID:

  13548

• Swiss Prot:

  Q61214

• Accession Number:

  Q61214

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Mouse Dyrk1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-745 amino acids from the C-terminal region of mouse Dyrk1a.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  85 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Dyrk1a

• NCBI Official Name:

  Dual specificity tyrosine-phosphorylation-regulated kinase 1A

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Park, J., et al. J. Biol. Chem. 285 (41) :31895-31906 (2010)

• Background Reference 02:

  Guo, X., et al. J. Biol. Chem. 285 (17) :13223-13232 (2010)

• Background Reference 03:

  Kurabayashi, N., et al. Mol. Cell. Biol. 30 (7) :1757-1768 (2010)

• Background Reference 04:

  Lee, Y., et al. J. Biol. Chem. 284 (48) :33343-33351 (2009)

• Other Product Names:

  Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Dual specificity YAK1-related kinase, MP86, Protein kinase minibrain homolog, MNBH, Dyrk1a, Dyrk

• Tested Applications:

  WB

• Physical Properties:

  Liquid