EDN2 Antibody

• Background :

  This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. [provided by RefSeq].

• NCBI Gene ID :

  1907

• Swiss Prot :

  P20800

• Accession Number :

  P20800

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This EDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-136 amino acids from the C-terminal region of human EDN2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  20 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  EDN2

• NCBI Official Name :

  Endothelin-2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02 :

  Darrah, R., et al. Physiol. Genomics 41 (1) :71-77 (2010)

• Background Reference 03 :

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Background Reference 04 :

  Menon, R., et al. Reprod. Biol. Endocrinol. 7, 62 (2009) :

• Other Product Names :

  Endothelin-2, ET-2, Preproendothelin-2, PPET2, EDN2

• Tested Applications :

  WB

• Protein ID :

  119615

• Physical Properties :

  Liquid