BCKDK Antibody

• Background:

  BCKDK belongs to the PDK/BCKDK protein kinase family. It contains 1 histidine kinase domain. BCKDK catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. BCKDK is the key enzyme that regulates the activity state of the BCKD complex.

• NCBI Gene ID:

  10295

• Swiss Prot:

  O14874

• Accession Number:

  NP_005872

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BCKDK.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store BCKDK antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  43 kDa

• Applications Notes:

  BCKDK antibody can be used for detection of BCKDK by ELISA at 1:62500. BCKDK antibody can be used for detection of BCKDK by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  BCKDK

• NCBI Official Name:

  Branched chain ketoacid dehydrogenase kinase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007) .

• Other Product Names:

  BCKDK, BDK, BCKDKD

• Tested Applications:

  ELISA, WB

• Protein ID:

  171906589

• Physical Properties:

  Liquid