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PIK3IP1 Antibody

CAT: 0223-57-275Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-275Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PIK3IP1 is a novel protein that shares homology with the p85 subunit of phosphatidylinositol-3-Kinases (PI3Ks) . The PI3K is essential for cell proliferation and Survival. The PIK3IP down regulates the activity of the PI3K and induces apoptosis by associating with p85 and p110 to form a complex, using the p85-like domain. However, there is no evidence to suggest that the PIK3IP1 prevents association of p85 and p110 as they associate with very high affinity.
NCBI Gene ID
113791
Swiss Prot
Q96FE7
Accession Number
Q96FE7
Host
Rabbit
Reactivity
Human
Immunogen
This PIK3IP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the C-terminal region of human PIK3IP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PIK3IP1
NCBI Official Name
Phosphoinositide-3-kinase-interacting protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Gao, P., et al. Beijing Da Xue Xue Bao 40 (6) :572-577 (2008)
Background Reference 02
He, X., et al. Cancer Res. 68 (14) :5591-5598 (2008)
Background Reference 03
Zhu, Z., et al. Biochem. Biophys. Res. Commun. 358 (1) :66-72 (2007)
Background Reference 04
Zhang, Z., et al. Protein Sci. 13 (10) :2819-2824 (2004)
Other Product Names
Phosphoinositide-3-kinase-interacting protein 1, Kringle domain-containing protein HGFL, PIK3IP1, HGFL
Tested Applications
WB
Protein ID
134034149
Physical Properties
Liquid

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