PIK3R1 Antibody

• Background:

  Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance.

• NCBI Gene ID:

  5295

• Swiss Prot:

  P27986

• Accession Number:

  P27986

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PIK3R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 558-587 amino acids from human PIK3R1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Immunology, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Xenopus, Bovine, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  84 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PIK3R1

• NCBI Official Name:

  Phosphatidylinositol 3-kinase regulatory subunit alpha

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kobayashi, H., et al., J. Biol. Chem. 279 (8) :6371-6379 (2004) .

• Background Reference 02:

  Liu, H., et al., J. Cell Biol. 164 (4) :603-612 (2004) .

• Background Reference 03:

  Sun, M., et al., J. Biol. Chem. 278 (44) :42992-43000 (2003) .

• Background Reference 04:

  Khan, N.A., et al., J. Neurovirol. 9 (6) :584-593 (2003) .

• Other Product Names:

  Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha, PIK3R1, GRB1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  118572681

• Physical Properties:

  Liquid