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GDI2 Antibody

CAT: 0223-57-273Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-273Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
NCBI Gene ID
2665
Swiss Prot
P50395
Accession Number
P50395
Host
Rabbit
Reactivity
Human
Immunogen
This GDI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the Central region of human GDI2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Symbol
GDI2
NCBI Official Name
Rab GDP dissociation inhibitor beta
NCBI Organism
Homo sapiens
Background Reference 01
Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)
Background Reference 02
Sun, Z.L., et al. Biochim. Biophys. Acta 1774 (6) :764-771 (2007)
Background Reference 03
Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)
Background Reference 04
Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)
Other Product Names
Rab GDP dissociation inhibitor beta, Rab GDI beta, Guanosine diphosphate dissociation inhibitor 2, GDI-2, GDI2, RABGDIB
Tested Applications
WB, IHC-P
Protein ID
13638228
Physical Properties
Liquid

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