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GDI1 Antibody

CAT: 0223-60-860Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-860Size:400 µL
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Background
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
NCBI Gene ID
2664
Swiss Prot
P31150
Accession Number
P31150
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This GDI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the C-terminal region of human GDI1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000-1:2000
Symbol
GDI1
NCBI Official Name
Rab GDP dissociation inhibitor alpha
NCBI Organism
Homo sapiens
Background Reference 01
Martins-de-Souza, D., et al.Psychiatr Res 44 (14) :989-991 (2010)
Background Reference 02
Massignan, T., et al. Mol. Cell Proteomics 9 (4) :611-622 (2010)
Background Reference 03
Chen, Y., et al. Biochem. J. 422 (2) :229-235 (2009)
Background Reference 04
Zhang, K.J., et al. Yi Chuan 30 (5) :590-594 (2008)
Other Product Names
Rab GDP dissociation inhibitor alpha, Rab GDI alpha, Guanosine diphosphate dissociation inhibitor 1, GDI-1, Oligophrenin-2, Protein XAP-4, GDI1, GDIL, OPHN2, RABGDIA, XAP4
Tested Applications
WB
Protein ID
1707886
Physical Properties
Liquid

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