TRPC5 Antibody

CAT: 0223-57-257Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-257Size:400 µL
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Background
This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na (+) -H+ exchange regulatory factor (NHERF), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1) .
NCBI Gene ID
7224
Swiss Prot
Q9UL62
Accession Number
Q9UL62
Host
Rabbit
Reactivity
Human
Immunogen
This TRPC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-283 amino acids from the N-terminal region of human TRPC5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
111 kDa
Fragment
Rabbit Ig
Symbol
TRPC5
NCBI Official Name
Short transient receptor potential channel 5
NCBI Organism
Homo sapiens
Background Reference 01
Al-Shawaf, E., et al. Arterioscler. Thromb. Vasc. Biol. 30 (7) :1453-1459 (2010)
Background Reference 02
Wong, C.O., et al. Pflugers Arch. 460 (1) :121-130 (2010)
Background Reference 03
Miehe, S., et al. J. Biol. Chem. 285 (16) :12426-12434 (2010)
Background Reference 04
Gross, S.A., et al. J. Biol. Chem. 284 (49) :34423-34432 (2009)
Other Product Names
Short transient receptor potential channel 5, TrpC5, Transient receptor protein 5, TRP-5, hTRP-5, hTRP5, TRPC5, TRP5
Tested Applications
WB, IHC-P
Protein ID
10720321
Physical Properties
Liquid

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