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TRPC7 Antibody

CAT: 0223-58-768Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-768Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity) . May also be activated by intracellular calcium store depletion.
NCBI Gene ID
57113
Swiss Prot
Q9HCX4
Accession Number
Q9HCX4
Host
Rabbit
Reactivity
Human
Immunogen
This TRPC7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 834-862 amino acids from the C-terminal region of human TRPC7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
100 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TRPC7
NCBI Official Name
Short transient receptor potential channel 7
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 02
Miyagi, K., et al. J. Biol. Chem. 284 (49) :34400-34412 (2009)
Background Reference 03
Graubert, T.A., et al. PLoS ONE (2), E4583 (2009) :
Background Reference 04
Abed, E., et al. Cell Prolif. 40 (6) :849-865 (2007)
Other Product Names
Short transient receptor potential channel 7, TrpC7, Transient receptor protein 7, TRP-7, hTRP7, TRPC7, TRP7
Tested Applications
WB
Protein ID
18202960
Physical Properties
Liquid

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