TRPC1 Antibody

• Background :

  TRPC1 belongs to the transient receptor potential (TRP) superfamily of cation channels. TRP cation channels are involved in diverse physiologic processes, including receptor- and store-operated Ca (2+) entry, mineral absorption, and cell death. They also function as sensors for pain, heat, cold, sound, stretch, and osmotic changes (Zhang et al., 2009 [PubMed 19193631]) .

• NCBI Gene ID :

  7220

• Swiss Prot :

  P48995

• Accession Number :

  P48995

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This TRPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 765-793 amino acids from the C-terminal region of human TRPC1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  91 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  TRPC1

• NCBI Official Name :

  Short transient receptor potential channel 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02 :

  Bomben, V.C., et al. Glia 58 (10) :1145-1156 (2010)

• Background Reference 03 :

  Lu, M., et al. J. Mol. Endocrinol. 44 (5) :285-294 (2010)

• Background Reference 04 :

  Gonzalez-Cobos, J.C., et al. Front. Biosci. 15, 1023-1039 (2010) :

• Other Product Names :

  Short transient receptor potential channel 1, TrpC1, Transient receptor protein 1, TRP-1, TRPC1, TRP1

• Tested Applications :

  WB

• Protein ID :

  1351302

• Physical Properties :

  Liquid