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TRPV5 Antibody

CAT: 0223-58-706Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-706Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.
NCBI Gene ID
56302
Swiss Prot
Q9NQA5
Accession Number
Q9NQA5
Host
Rabbit
Reactivity
Human
Immunogen
This TRPV5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 634-663 amino acids from the C-terminal region of human TRPV5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
83 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TRPV5
NCBI Official Name
Transient receptor potential cation channel subfamily V member 5
NCBI Organism
Homo sapiens
Background Reference 01
Chamoux, E., et al. J. Biol. Chem. 285 (33) :25354-25362 (2010)
Background Reference 02
Kennedy, B.G., et al. Mol. Vis. 16, 665-675 (2010) :
Background Reference 03
Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)
Background Reference 04
De Groot, T., et al. J. Am. Soc. Nephrol. 20 (8) :1693-1704 (2009)
Other Product Names
Transient receptor potential cation channel subfamily V member 5, TrpV5, Calcium transport protein 2, CaT2, Epithelial calcium channel 1, ECaC, ECaC1, Osm-9-like TRP channel 3, OTRPC3, TRPV5, ECAC1
Tested Applications
WB
Protein ID
62901471
Physical Properties
Liquid

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