TRPC4 Antibody

• Background:

  TRPC4 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC4 probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It has also been shown to be calcium-selective. TRPC4 may also be activated by intracellular calcium store depletion.

• NCBI Gene ID:

  7223

• Swiss Prot:

  Q9UBN4

• Accession Number:

  NP_057263

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRPC4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  293T Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TRPC4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  112 kDa

• Applications Notes:

  TRPC4 antibody can be used for detection of TRPC4 by ELISA at 1:312500. TRPC4 antibody can be used for detection of TRPC4 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TRPC4

• NCBI Official Name:

  Transient receptor potential cation channel, subfamily C, member 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Odell, A.F., (2008) J. Biol. Chem. 283 (7), 4395-4407.

• Other Product Names:

  TRPC4, HTRP4, MGC119570, MGC119571, MGC119572, MGC119573, TRP4, HTRP-4

• Tested Applications:

  ELISA, WB

• Protein ID:

  7706747

• Physical Properties:

  Liquid