NKD1 Antibody

• Background:

  In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365) -binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820) -beta-catenin (see MIM 116806) -Tcf (see MIM 602272) signaling pathway.

• NCBI Gene ID:

  85407

• Swiss Prot:

  Q969G9

• Accession Number:

  Q969G9

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This NKD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the N-terminal region of human NKD1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  52 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  NKD1

• NCBI Official Name:

  Protein naked cuticle homolog 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Guo, J., et al. PLoS ONE (11), E7982 (2009) Creyghton, M.P., et al. Proc. Natl. Acad. Sci. U.S.A. 103 (14) :5397-5402 (2006) Creyghton, M.P., et al. Genes Dev. 19 (3) :376-386 (2005) Yan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 98 (26) :14973-14978 (2001) Katoh, M. Int. J. Oncol. 19 (5) :963-969 (2001)

• Other Product Names:

  Protein naked cuticle homolog 1, Naked-1, hNkd, hNkd1, NKD1, NKD

• Tested Applications:

  WB

• Protein ID:

  74731040

• Physical Properties:

  Liquid