NKD2 Antibody

• Background:

  In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365) -binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820) -beta-catenin (see MIM 116806) -Tcf (see MIM 602272) signaling pathway.

• NCBI Gene ID:

  85409

• Swiss Prot:

  Q969F2

• Accession Number:

  Q969F2

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NKD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-393 amino acids from the C-terminal region of human NKD2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  50 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  NKD2

• NCBI Official Name:

  Protein naked cuticle homolog 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hu, T., et al. J. Biol. Chem. 285 (18) :13561-13568 (2010)

• Background Reference 02:

  Ding, W., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (36) :13433-13438 (2008)

• Background Reference 03:

  Li, C., et al. Mol. Biol. Cell 18 (8) :3081-3093 (2007)

• Background Reference 04:

  Adamowicz, M., et al. Genes Chromosomes Cancer 45 (9) :829-838 (2006)

• Other Product Names:

  Protein naked cuticle homolog 2, Naked-2, hNkd2, NKD2

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  74716653

• Physical Properties:

  Liquid