MKL2 Antibody

• Background:

  MKL2 acts as a transcriptional coactivator of serum response factor (SRF) . Required for skeletal myogenic differentiation.

• NCBI Gene ID:

  57496

• Swiss Prot:

  Q9ULH7

• Accession Number:

  Q9ULH7

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This MKL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of human MKL2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  118 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MKL2

• NCBI Official Name:

  MKL/myocardin-like protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Huang, D., et al. Genes Chromosomes Cancer 49 (9) :810-818 (2010)

• Background Reference 02:

  Holt, R., et al. Eur. J. Hum. Genet. 18 (9) :1013-1019 (2010)

• Background Reference 03:

  Medjkane, S., et al. Nat. Cell Biol. 11 (3) :257-268 (2009)

• Background Reference 04:

  Lagna, G., et al. J. Biol. Chem. 282 (51) :37244-37255 (2007)

• Other Product Names:

  MKL/myocardin-like protein 2, Megakaryoblastic leukemia 2, Myocardin-related transcription factor B, MRTF-B, MKL2, KIAA1243, MRTFB

• Tested Applications:

  WB

• Protein ID:

  32363203

• Physical Properties:

  Liquid