MCF2 Antibody

• Background:

  The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.

• NCBI Gene ID:

  4168

• Swiss Prot:

  P10911

• Accession Number:

  P10911

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MCF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 804-833 amino acids from the C-terminal region of human MCF2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  108 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MCF2

• NCBI Official Name:

  Proto-oncogene DBL

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Piton, A., et al. Mol. Psychiatry (2010) In press :

• Background Reference 02:

  Murakami, M., et al. Int. J. Cancer 123 (3) :500-510 (2008)

• Background Reference 03:

  Murakami, M., et al. Cancer Biol. Ther. 7 (5) :677-688 (2008)

• Background Reference 04:

  Rojas, R.J., et al. J. Biol. Chem. 282 (40) :29201-29210 (2007)

• Other Product Names:

  Proto-oncogene DBL, Proto-oncogene MCF-2, MCF2-transforming protein, DBL-transforming protein, MCF2, DBL

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  92087039

• Physical Properties:

  Liquid